Brighton and Hove Albion take on the Toon live on ITV as the club look for a fifth win on the bounce.
Head coach Fabian Hürzeler has named a strong side, with Bart Verbruggen in goal, Adam Webster as captain at centre back and Joao Pedro and Georginio Rutter up front.
Club captain Lewis Dunk remains sidelined by injury but Jack Hinshelwood is in the starting line up, as are Tariq Lamptey, former Magpie Yakuba Minteh and Kaoru Mitoma.
Danny Welbeck is on the bench, along with the likes of Solly March, Simon Adingra and Diego Gomez.
Former Seagull Dan Burn is down to start for the hosts, alongside the likes of Alexander Isak, Antony Gordon and Joelinton.
Albion have knocked Newcastle out of the FA Cup four times – in 1983, 1986, 2012 and 2013 – and suffered their only reverse 95 years ago in 1930.
The match is due to kick off at 1.45pm today (Sunday 2 March).
