Journalists at The Argus newspaper have voted to go on strike next week over pay and the latest round of redundancies.
The National Union of Journalists organised the ballot, with 82.8 per cent of members taking part.
Of those, 91 per cent voted to strike.
The strike is scheduled to take place next Thursday and Friday (18 and 19 November).
Next Friday (19 November) is the last day for six news sub-editors working at the title which serves Brighton and Hove from its offices in Crowhurst Road, Hollingbury.
Their jobs are being made redundant, with the work being taken on by three subs in Southampton at the offices of the Southern Daily Echo.
The Argus closed its press hall last year, with the printing now also carried out in Southampton.
Newsquest has frozen staff pay for more than two years.
Staff at the Echo were on strike yesterday and today, with another 48-hour strike scheduled for Tuesday and Wednesday next week too (16 and 17 November).
One Argus journalist, who asked not to be named, said: “It’s high time we Argonauts stood up to the disgraceful management which keeps taking from Brighton and not giving anything back.
“Job after job has been moved to Southampton in a bid to scrimp and save.
“The bosses blame difficult trading conditions but meanwhile they boast about making massive profit margins – about 20 per cent – and give the chief executive a £100,000 21 per cent pay rise.
“Enough is enough.”
Newsquest Sussex declined to comment.