A date has been set to decide the biggest planning application in Brighton since the Falmer Stadium.
The future of the Royal Sussex County Hospital in Eastern Road in Kemp Town will be decided on Friday 27 January.
Brighton and Hove City Council will hold a Special Planning Committee meeting at Hove Town Hall to back or block the £420 million scheme.
The proposal – by Brighton and Sussex University Hospitals NHS Trust – involves demolishing the original Barry Building which dates from the 1820s. The 19th century Jubilee Building would also be replaced.
The trust expects the scheme to take ten years to complete and is part of a project known as the 3Ts project. It involves turning the Royal Sussex into a regional centre of excellence.
Unusually the scheme will not be paid for through a Private Finance Initiative (PFI) arrangement. Earlier PFI-funded projects have been criticised for saddling hospitals with debts.