Brighton & Hove Albion 0 Manchester United 0
(Manchester United win 7-6 on penalties)
Albion lost a sudden-death penalty shoot-out, with Solly March missing the vital seventh spot kick, blazing his penalty over the bar.
Victor Lindelof scored the decisive penalty to send United through to the FA Cup final against Manchester City on Saturday 3 June.
Brighton had chances in normal time, most notably falling to March and Deniz Undav. And a Julio Enciso effort from the edge of the area saw David De Gea miraculously turn the effort over with his fist.
Brighton began on the front foot at Wembley, where Mac Allister hit a brilliant sixth-minute free-kick that De Gea did well to stop nestling in the top right-hand corner.
Enciso struck wide before Kaoru Mitoma and Pervis Estupinan got in each other’s way as Albion continued in the ascendancy with only fleeting flickers of life from United.
Bruno Fernandes, sorely missed against Sevilla, forced Robert Sanchez into action from 20 yards and was soon the subject of nervous conversation after pulling up in pain. The patched-up Portuguese star was given the green light to carry on.
Enciso fired wide for Brighton but it was United who ended the half on top, with Fernandes dragging a shot across the face of goal.
Two further chances followed in stoppage time. Anthony Martial overhit an attempt to catch out Sanchez and Eriksen fired straight at the keeper from a Rashford cross.
Brighton returned from the break strongly, prodding and probing before De Gea denied them a 56th-minute goal.
Adam Webster and Mitoma were denied in quick succession before the ball fell to Enciso to fizz an effort that the United goalkeeper expertly tipped over.
Ex-United striker Danny Welbeck went close with a header from the resulting corner and De Gea was soon called upon to stop a March cross-shot.
United belatedly gained a measure of control and composure, with Sanchez denying Antony before Fernandes fired a free-kick at the wall from a dangerous position.
De Gea got down to push away a low March shot and substitute Jadon Sancho saw a curling effort deflected behind.
When extra time got under way, Brighton substitute Deniz Undav was guilty of a heavy touch at the end of a fine move before Marcel Sabitzer glanced wide and fellow substitute Fred caused problems.
First the Brazil midfielder sent over a dangerous cross that nobody met, before cutting out the ball as Rashford ended up getting away a strike that took a deflection off Webster and was saved superbly by Sanchez.
The second period also ended goalless. March saw a shot stopped and Rashford lashed across the face of goal, with Brighton just unable to squeeze home a late chance that ended with Mitoma leaving De Gea in a heap.
The final whistle saw attention turn to penalties, with each player finding the net in the first five rounds.
Sancho and Rashford showed character to score at the stadium where they missed spot-kicks in England’s Euro 2020 final loss to Italy, with Sanchez getting a hand on Marcel Sabitzer’s fifth attempt for United.
Webster and Wout Weghorst scored the first goals of sudden death, only for March to miss in front of the Brighton end and Lindelof to score the decider.