Brighton police were called out twice to two separate reports of squatters causing a disturbance.
The first was at the empty Fat Leo restaurant in Market Street at 2.14am.
The property has just been let again, and the News understands it is about to undergo a refurbishment.
Windows were smashed and loud music and other noises were heard coming from inside, believed to be a fight.
But when police arrived, everything was in order.
They were called out again to the former She Said erotic boutique in Ship Street Gardens at about 3.30am.
A police spokeswoman said: “Police received a report that squatters had broken into a building in Ship Street Gardens, Brighton, at 3.28am on Monday (9 February).
“When police arrived it was established that a window had been smashed at the building but there were no squatters.”
The Brighton and Hove News understands the owner got them to leave and then drilled doors and windows shut.
The She Said boutique relocated to a new shop in Ship Street last month.
By this morning, there was no sign of them.
In April last year, police raided a squat in the former Choccywoccydoodah shop in Duke Street after a man was found with head and ear injuries.